第39回日本脳腫瘍病理学会

海外招待演者/Invited speaker

Dr. Fausto Jose Rodriguez

Assistant professor of pathology and oncology at the Johns Hopkins University School of Medicine

Dr. Fausto Jose Rodriguez

His clinical expertise lies in the identification of diagnostic, prognostic and therapeutic biomarkers in primary brain tumors.

Dr. Rodriguez earned his M.D. from the University of Missouri. He completed a residency in anatomic pathology and a fellowship in neuropathology at the Mayo Medical School College of Medicine.

His current research focuses on the pathology of pediatric gliomas and the phenotypic characterization of murine models of central nervous system neoplasia.

Dr. Rodriguez has published extensively and is board certified in anatomic pathology and neuropathology.

Publications

  • Rodriguez FJ, Orr B, Ligon K, Eberhart CG. “Neoplastic cells are a rare component in human glioblastoma microvasculature.” Oncotarget 2012;3:98-106.
  • Rodriguez EF, Scheithauer BW, Giannini C, Rynearson A, Cen L, Hoesley B, Gilmer-Flynn H, Sarkaria JN, Jenkins S, Long J, Rodriguez FJ. “PI3K/AKT Pathway Alterations are Associated With Clinically Aggressive and Histologically Anaplastic Subsets of Pilocytic Astrocytoma.” Acta Neuropathol 2011;121:407-20.
  • Bender AM, Collier LS, Rodriguez FJ, Tieu C, Larson JD, Halder C, Mahlum E,. Kollmeyer TM, Akagi K, Sarkar G, Largaespada DL, Jenkins RB. “Sleeping Beauty-mediated somatic mutagenesis implicates Csf1 in the formation of high grade astrocytomas.” Cancer Res 2010; 70:3557-65.
  • Rodriguez FJ, Giannini C, Asmann YW, Sharma MK, Perry A, Tibbetts KM, Jenkins RB, Scheithauer BW, Anant S, Jenkins S, Eberhart CG, Sarkaria JN, Gutmann DH. “Gene Expression Profiling of NF1-associated and Sporadic Pilocytic Astrocytoma Identifies ALDH1L1 as an Underexpressed Candidate Biomarker in Aggressive Astrocytoma Subtypes.” J Neuropathol Exp Neurol 2008;12:1194-1204
  • Rodriguez FJ, Gamez JD, Vrana JA, Theis JD, Giannini C, Scheithauer BW, Parisi J, Lucchinetti CF, Pendlebury WW, Dogan A. “Immunoglobulin Derived Depositions in the Nervous System: Novel Mass Spectrometry Application for Protein Characterization in Formalin-Fixed Tissues.” Lab Investig 2008;88:1024-37.

Felix Sahm, MD, PhD

Heidelberg University

Felix Sahm, MD, PhD

Felix Sahm, MD, PhD, graduated from University Heidelberg Medical School in 2009 after studying in Heidelberg, Boston, and London. He conducted the research for his MD thesis in the Department of Neurooncology Heidelberg (Prof Wolfgang Wick) in the group of Prof Michael Platten, working on glioma-promoting effects of tryptophan degradation (Opitz, Litzenburger, Sahm et al., Nature 2011). He subsequently started his residency in the Department of Neuropathology led by Prof Andres von Deimling at the University Hospital Heidelberg, being also affiliated with the Clinical Cooperation Unit Neuropathology at the German Cancer Research Center (DKFZ) as postdoc researcher.

In 2016, he was board-certified in Neuropathology, which is an independent discipline in Germany and requires a minimum residency of six years. In parallel, he pursued his Habilitation under the mentorship of Prof Andreas von Deimling. This was completed by being awarded the venia legendi in Clinical Neuropathology by the Medical Faculty Heidelberg in 2017. He currently serves as managing consultant and head of the Division Molecular Neuropathology at the Dept. of Neuropathology Heidelberg, providing molecular testing by targeted panel and RNA sequencing and DNA methylation array for diagnostic routine and several clinical trials with collaboration partners Profs Wolfgang Wick, Michael Platten, and Stefan Pfister. He has contributed to >100 publications in peer reviewed journals. These include his study elucidating that gliomas histologically presenting as oligoastrocytoma can molecularly be assigned to either astrocytoma or oligodendroglioma, the implementation of the first brain tumor-specific hybrid-capture next-generation-sequencing panel, the study establishing the prognostic role of TERT promoter mutations in meningioma, or a proposal for an epigenetic classification of meningioma subgroups. His research focus is molecular pathology of glioma and meningioma, with special interest in identifying novel clinically meaningful.

事務局

宮崎大学医学部臨床神経科学講座脳神経外科学分野
〒889-1692 宮崎県宮崎市清武町木原5200
TEL:0985-85-3128

連絡事務局

株式会社コンベックス内
〒105-0001 東京都港区虎ノ門5-12-1
TEL:03-5425-1604 FAX:03-5425-1605
E-mail:btp39@convex.co.jp

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